Obesity, Racism and Covid: A Deadly Combination
Social determinants of health contribute to higher rates of obesity among Black, Hispanic and Native American women. And that makes Covid more dangerous for them.
In the earliest days of the Covid pandemic, the people who were most likely to be hospitalized or die from the virus had a few things in common.
Age was the greatest risk factor for becoming very sick with Covid. Race and ethnicity also seemed to have a connection, as Covid deaths were higher among Black, Hispanic and Native American people.
Having two or more health conditions (called comorbidities) — increased the risk of severe illness and death from Covid. But some of the comorbidities you hear a lot about, such as asthma, heart disease, lung disease and diabetes, weren’t the ones that gave Covid patients the highest risk of hospitalization and death.
It was obesity.
“Obesity is a disease characterized by a chronic inflammatory process, and that process had a major collision with multiple factors during the pandemic,” said
Fatima Cody Stanford, M.D., M.P.H., M.P.A., an associate professor of medicine at Massachusetts General Hospital and an obesity medicine physician scientist. “Covid is an acute inflammatory process, and these two things [Covid and obesity] don’t play so well together.”
Studies show that social determinants of health — the conditions in the environments where people are born, live, learn, work, play, worship and age — made the virus worse for people living with obesity. Covid was also worse for people of color. In her 2021 TEDx talk, Cody Stanford said people of color were battling three pandemics — obesity, racism and Covid-19.
Read: Social Determinants of Health, Health Disparities and Health Equity >>
The way obesity works provides insight as to why Covid proved so deadly.
“One very simple reason was that patients with obesity cannot expand their lungs that much,” said Holly F. Lofton, M.D., director of the medical weight management program at NYU Langone Health and a member of HealthyWomen’s Women’s Health Advisory Council. “If you add a respiratory illness like Covid to a condition where you already can't expand your lungs, the mucus starts to build, and it’s really hard to expel it.”
Lofton noted people with obesity usually have a higher waist circumference, defined as more than 35 inches in a female or 40 inches in a male. That midsection weight pushes on the diaphragm, making the chest cavity around the lungs smaller. For a patient with Covid, that smaller chest cavity leaves less room to breathe when breath is needed most.
Fat itself causes inflammation. Fat cells release cytokines, which are inflammatory hormones that can make immune function worse. People with obesity have high levels of one of those cytokines (Interleukin-6 or IL-6), and high levels of IL-6 were associated with poor outcomes in Covid patients.
The inflammation from obesity is also a risk factor for blood clots forming. Lofton said she warns people living with obesity who are otherwise healthy before having weight loss surgery about the risk of clots forming. Blood clots can happen in response to infection or lack of movement. Blood could be more likely to clot as a reaction to inflammation from Covid, and when clots travel to arteries and veins in the organs, it can lead to heart attack, stroke, organ damage or death.
Obesity is a disease. One study from the Centers for Disease Control and Prevention (CDC) tracking obesity rates found that Black/African American women had the highest rates of obesity compared to any other racial group at 57%. Among Hispanic women, 44% were living with obesity. Non-Hispanic white women had a 40% obesity rate, while Asian women had the lowest rates of obesity at 17%. A different study showed that 48% of all Native Americans had obesity.
Like other diseases, obesity is affected by social determinants of health, with many of the following factors contributing to its development.
If you have obesity, you can do your best to protect yourself from Covid-19 by staying up to date on Covid vaccines and taking preventive measures when in public, like wearing a face mask and washing your hands frequently or using hand sanitizer. You can also improve your outcome by testing immediately if you have symptoms and contacting your HCP as soon as you suspect Covid to get timely treatment.
You may not be able to control many of the factors that contribute to getting sick from Covid. But studies suggest that obesity treatment can improve your overall health and reduce the risk of poor outcomes from Covid. One study found that patients who had had weight loss surgery had a 60% lower risk of developing severe Covid complications.
In addition to preventive measures, Lofton stressed the importance of continuing education for HCPs to help eliminate weight bias in healthcare.
“Physicians need to be made aware that there’s unconscious weight bias, and that we should try to put that to the side when treating patients with obesity,” Lofton said.
Cody Stanford said her focus is improving overall health to help decrease chronic inflammation that leads to obesity and makes other diseases, such as Covid, more dangerous, while recognizing the intersection of race and class in overall outcomes.
“My goal is to get people to a happier, healthier state of being,” she said. “It’s not about giving them a number on a scale, but looking at cholesterol values, fasting blood sugar, insulin values, liver function — let’s look at all of that together. I emphasize the health piece of the puzzle, and helping prevent all of the diseases that obesity can cause.
This resource was created with support from Pfizer.





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