- What is it?
- Birth Control Pills
- Long-Acting Hormonal Methods
- Barrier Methods
- Natural Family Planning
- Permanent Contraception
- Facts to Know
- Questions to Ask
- Key Q&A
- Organizations and Support
What is it?
What Is It?
Contraception refers to a woman's chosen form of birth control, including hormonal, barrier, chemical and natural methods.
Choosing a birth control method is one of the most personal health care decisions a woman makes. In nearly four decades of childbearing years, your need for birth control will most likely change many times. But at each life stage, you can make informed decisions by learning about all your contraceptive options and selecting one or more that best fits your reproductive health needs.
Many women are not adequately protected from an unwanted pregnancy by their choice of birth control method. In fact, according to the Guttmacher Institute, about one-half of all pregnancies in the United States are unplanned.
There are several reasons for failure of contraception, including inappropriate use (for example, not inserting a diaphragm the right way or not using enough spermicide); failure to continue use of the method (for example, forgetting to take your birth control pills or not using a condom every time you have sex); and failure of the contraceptive method itself.
Of the women who experience unplanned pregnancies each year in the United States, 41 percent use birth control, but these women use birth control inconsistently. Of women who use birth control consistently, only 5 percent become pregnant per year. This illustrates the importance of consistent birth control use.
Myths or personal concerns about the risks and safety of certain birth control options also contribute to incorrect use of birth control. Women may use a particular method only occasionally, for example, thinking that less frequent use is safer than continuous use. Or they may stop using a particular method because of bothersome side effects.
Age-related changes can lead women to believe they no longer need to use contraception. For example, women nearing menopause may mistakenly think they are no longer fertile because their menstrual cycles are no longer regular. However, according to the American Congress of Obstetricians and Gynecologists (ACOG), about 75 percent of pregnancies in women over 40 are unintended. Although menopause does mark the end of a woman's childbearing years, you have not gone through menopause until 12 consecutive months without a period. You can get pregnant even if your periods are irregular.
Today, American women have more contraceptive options to choose from than ever before. So you should be able to find one that works well for you and fits your lifestyle.
Other things to consider before making a contraception choice:
- Find out how much the contraceptive costs. Most oral contraceptives and some other contraceptives are now free under the Affordable Care Act, but check with your insurance provider to be sure.
- Ask yourself if you can realistically use this method. Are you sure you understand how to use it properly? Will this method embarrass you or your partner? Does it fit with your lifestyle?
- Find out how to use the method correctly and what to do if you forget to use it occasionally.
- Ask your health care professional about side effects. What should you expect? What should you do about them if they occur, and when should you expect them to stop?
- Will this method cause any unacceptable weight gain?
You can probably think of many more questions about birth control. Learn as much as you can about your options and make an informed decision about which method is the best and safest for you. Consider your needs and discuss them with your health care professional during your next medical appointment.
To get you started, here is some basic information about contraceptive options approved by the U.S. Food and Drug Administration (FDA), and resources you can use for more in-depth research.
For a comparison of how effective each type of contraception is for preventing pregnancy, please see the chart, "Contraceptive Failure Rates" at the end of this entry.
The contraceptive options women may choose are:
- Birth control pills, also called oral contraceptives
- Hormonal contraceptive patches
- Hormonal contraceptive vaginal rings
- Long-acting hormonal methods, such as shots and implants
- Intrauterine devices (IUDs)
- Barrier methods such as condoms, diaphragms, contraceptive sponges and cervical caps
- Permanent contraception (sterilization)
Remember that most methods of birth control do not protect against sexually transmitted diseases (STDs) such as HIV, gonorrhea, chlamydia, genital herpes and human papillomavirus (HPV). Latex condoms, when used consistently and correctly, provide the best available means of reducing the risk of many STDs, according to the United States Centers for Disease Control and Prevention. If you are not in an exclusive relationship with someone who has been tested for STDs, you should use condoms along with any other form of birth control.
Birth Control Pills
There are three types of BCPs on the market today: the combination pill, the mini-pill and the emergency contraceptive pill. The combination pill is the most widely prescribed. It contains two hormones: estrogen and progestin. It works by suppressing ovulation each month.
Learn more: Birth Control Pills
Long-Acting Hormonal Methods
Several options are available to women who want long-term, but not permanent, protection against pregnancy, including intrauterine devices, hormonal patches and vaginal rings. These options rely on estrogen-progestin or progestin alone to prevent ovulation.
Learn more: Long-Acting Hormonal Methods
Barrier methods are less effective than hormonal methods but cause fewer side effects and are associated with less risk. They include condoms, diaphragms, the contraceptive sponge and cervical caps
Learn more: Barrier Methods
Natural Family Planning
A calendar, body temperature and physical symptoms, such as the consistency of cervical mucus, are used to determine when ovulation is likely, and you avoid intercourse during this time.
Learn More: Natural Family Planning
Female sterilization closes a woman's fallopian tubes by blocking, tying or cutting them so an egg cannot travel to the uterus.
Learn more: Permanent Contraception
The Effectiveness of Contraceptives
The statistics below represent the percentage of women who experienced unintended pregnancy during one year of using the contraceptive method indicated.
Hormone Shot (Depo-Provera)
Combined Pill (Estrogen/Progestin)
Minipill (Progestin only)
Three-month pill (Seasonale, Seasonique)
Patch (Ortho Evra)
Ring (Nuva Ring)
Less than 1%
Less than 2%
Less than 1%
Less than 1%
|Intrauterine Devices (IUDs): |
Male Latex Condom(*)
Cervical Cap (no previous births)(**)
Cervical Cap (previous births)(**)
18-28% (higher failure rate after childbirth)
|Spermicide: (gel, foam, suppository, film) ||26%|
Natural Family Planning (calendar, temperature, cervical mucus)
*used without spermicide
**used with spermicide
Birth Control Pills
Birth Control Pills (BCPs)
There are three types of birth control pills on the market today: the combination pill, the mini-pill and the emergency contraceptive pill.
The combination pill is the most widely prescribed. It contains two hormones: estrogen and progestin. It works by suppressing ovulation each month, thinning the uterine lining and changing the consistency of the mucus in a woman's cervix, making it harder for sperm to move into contact with an egg.
Low-dose combination birth control pills contain 10 to 50 mcg of estrogen, a lower dose (one-fourth or less) than the birth control pills marketed 30 to 50 years ago. They come in different formulations. Some require taking a constant dose of both medications for 21 days followed by one week of placebo tablets. Others vary the dose of estrogen and/or progestin that a woman gets throughout her cycle (multiphasic) or add additional days (tablets) of estrogen at the end of the 21- or 24-day cycle.
The FDA also has approved continuous-use birth control pills that contain ethinyl estradiol and levonorgestrel. Brand names include Lybrel, Alesse, Lessina, Nordette and others. It is a monophasic pill (containing the same levels of estrogen and progestin throughout the entire pill-taking schedule) that comes in a 28- or 21-day pack and is designed to be taken continuously, with no break between pill packets. That means you won't have a period. You may have some spotting or breakthrough bleeding, particularly when you first start using continuous birth control pills. But most women will have no bleeding (or hardly any) by the end of a year.
Seasonale is a 91-day oral contraceptive regimen also designed to reduce the number of months you have a menstrual cycle. Tablets containing progestin and estrogen are taken for 12 weeks (84 days), followed by one week of placebo tablets. Therefore, the number of expected menstrual periods is reduced from once a month to about once every three months, or four times a year. Seasonique is the same as Seasonale except with Seasonale, women take inactive pills during their four yearly periods and with Seasonique, they take a low dose of estrogen during their periods. Recently, Lo-Seasonique was approved by the FDA as well. It is similar to Seasonique but with lower doses of hormones.
If and when you decide to get pregnant and stop taking birth control pills, you may get pregnant immediately—there are no long-term effects on your fertility from birth control pills.
Benefits. Birth control pills are now also prescribed by health care professionals because of their long- and short-term health benefits for women. Birth control pills can help:
- Regulate, shorten or eliminate a woman's menstrual cycle
- Decrease severe cramping and heavy bleeding
- Reduce anemia
- Reduce ovarian cancer risk. According to the American Cancer Society, women who have taken birth control pills for five years or more have about half the risk of ovarian cancer compared to women who have never taken the pill.
- May reduce colorectal cancer risk.
- Reduce the development of ovarian cysts
- Decrease benign breast disease
- Provide reliable birth control without affecting future ability to become pregnant
- Reduce the severity and incidence of pelvic inflammatory disease (PID)—infection primarily of the fallopian tubes and/or the female reproductive tract
- Protect against ectopic pregnancy (pregnancy outside the uterus, in the fallopian tubes)
- Reduce the risk of uterine (endometrial) cancer. Studies find that oral contraceptives protect against this disease by providing the progestins needed to oppose the stimulation of the uterine lining caused by estrogen. The risk is lowest in women who have taken the pill for a long time, and it appears to continue for at least 10 years after a woman has stopped taking the pill.
- Minimize perimenopausal symptoms, such as irregular menstrual bleeding
- Reduce acne
- Treat the emotional and physical symptoms of premenstrual dysphoric disorder (PMDD), a severe form of PMS. Two combination oral contraceptives—called Yaz and Beyaz—have been approved by the FDA for use as an oral contraceptive and as a treatment for the emotional and physical symptoms of PMDD. Both Yaz and Beyaz contain the progestin drospirenone and ethinyl estradiol, a form of estrogen. Beyaz also contains folic acid.
Risks. Women with certain health conditions may not be able to use birth control pills. These include:
- Heart disease or stroke
- Liver disease
- Blood clots in the deep veins or lung (risk may vary by formulation so check with your provider)
- Breast cancer
- Severe or uncontrolled diabetes. The estrogen in birth control pills may increase glucose levels and decrease the body's insulin response, while the progestin in the pills may encourage overproduction of insulin. Use of birth control pills by diabetic women should be limited to those who do not smoke, are younger than 35 and are otherwise healthy with no evidence of persistent high blood pressure, kidney disease, vision problems or other vascular disease.
- Smokers 35 or older. Women age 35 or older who smoke and take birth control pills have a significantly higher risk of ischemic stroke.
- Certain types of migraine headaches. Women who take birth control pills and have a history of migraines have an increased risk of stroke compared to nonusers with a history of migraine. Your risk is greatest if you have migraines with "aura"—blurred vision, temporary loss of vision or seeing flashing lights or zigzag lines. As a result, the World Health Organization (WHO) has concluded that women with migraines with aura should not take birth control pills. For women over age 35 who get migraines without aura, the risks of oral contraceptive use usually outweigh the benefits. For women under 35, ACOG gynecologists and the WHO state that combined birth control pills may be considered for women with migraines only if they do not experience aura, do not smoke and are otherwise healthy.
- Severe hypertension. Birth control pill users with a history of high blood pressure faced a substantially higher relative risk of ischemic stroke (blood clot in the brain) than nonusers with no such history. Oral contraceptives have been associated with a small, but significant increase in ischemic stroke risk in many, but not all, studies. This was a particular concern with early birth control pills that contained higher doses of estrogen, but newer pills containing less estrogen are associated with a lower risk of stroke than high-dose pills. In otherwise healthy young women (nonsmokers without persistent high blood pressure), the risk is low.
Smoking cigarettes while taking birth control pills dramatically increases risks of heart attack and stroke for women over age 35. Smoking is far more dangerous to a woman's health than taking birth control pills, but the combination of oral contraceptive pill use and smoking has a greater effect on heart attack and stroke risk than the simple addition of the two factors.
Some women worry that birth control pills may increase their risk for cancer, particularly breast cancer. Research has shown women using birth control pills have a slightly higher risk of breast cancer than women who never used them. Newer low-estrogen birth control pills do not carry the risk of increased breast cancer that higher-dose estrogen pills did. An August 2014 study published in Cancer Research that looked at breast cancer risk and birth control pill use in women ages 20 to 49 found breast cancer risk was higher in women who had previously taken high-dose estrogen birth control pills, but not in women who had taken low-dose estrogen pills.
Discuss the risks and benefits of birth control pills with your health care professional.
There is some evidence that long-term use of birth control pills may increase the risk of cancer of the cervix (the narrow, lower portion of the uterus). There is also some evidence that birth control pills may increase the risk of certain benign (noncancerous) liver tumors.
Side effects and warnings. Nausea, breast tenderness and bleeding are the most common side effects of all birth control pills. Most side effects decrease or disappear after three months of continuous use. Switching to another pill formulation can also relieve side effects.
A serious issue often overlooked by both health care professionals and women is that interactions with other medications can reduce the effectiveness of birth control pills. Medications known to interact with birth control pills are rifampin (an antibiotic) and some anticonvulsants. If you take these drugs regularly but are still interested in using the pill as your birth control method, talk with your health care professional.
A second birth control pill option is referred to as the "mini-pill." One pill, which contains only progestin, is taken every day. These pills work by preventing ovulation and thickening cervical mucus to prevent sperm from reaching the egg. They also keep the uterine lining from thickening, which prevents a fertilized egg from implanting in the uterus. However, with progestin-only birth control pills, ovulation isn't consistently suppressed, so the actions on cervical mucus and the endometrium are the critical factors. They may not be as effective as combined birth control pills. Progestin-only pills must be taken at exactly the same time, every day.
However, the progestin-only pill is often an option if you want to use oral contraception but can't take estrogen or have a history of or increased risk of estrogen-related blood clots. If you are breastfeeding or experience uncomfortable side effects from estrogen, such as headaches, this could be the best option for you.
Protection against ectopic pregnancy is not as strong with the mini-pill as it is with combination pills. The main side effect from mini-pills is menstrual irregularity; you may not have any bleeding for months or you may have some spotting between periods. As with combined birth control pills, the mini-pill does not protect you from sexually transmitted diseases, so condoms are necessary if you or your partner is at risk.
This type of contraception is used after unprotected intercourse or failure of a barrier method. Emergency contraceptive pills contain the same hormones as birth control pills. In fact, some birth control pills can be used as emergency contraception with a health care professional's guidance. Emergency contraceptive pills should not be used for routine birth control.
Commonly called "the morning after pill," there are several FDA-approved emergency contraception pills in the United States: Plan B One-Step, Next Choice and generic levonorgestrel tablets, all of which contain the progestin levonorgestrel, and ulipristal acetate tablets, sold under the brand name "ella."
ella can prevent pregnancy when taken orally within five days (120 hours) after unprotected sex. It is a progesterone agonist/antagonist whose likely main effect is to inhibit or delay ovulation. ella cuts the chances of becoming pregnant by about two-thirds for at least 120 hours after unprotected sex, studies have shown.
Plan B One-Step should be taken within 72 hours of unprotected sex. Recent research shows that the levonorgestrel pills may be effective up to 120 hours after unprotected sex but are more effective the sooner they are taken. Next Choice and generic levonorgestrel tablets works similarly to Plan B One-Step, but consists of a two-dose regimen, with the first dose taken within 72 hours of unprotected sex and the second 12 hours later. Newer studies indicate that both pills may be taken together as soon as possible after unprotected sex.
You can buy the levonorgestrel emergency contraceptive pills over the counter without a prescription. You must ask for them at the pharmacy counter. ella is available only by prescription, but women could keep a supply at home.
For information on emergency contraception, visit www.not-2-late.com or call 1-888-NOT-2-LATE or 1-800-230-PLAN to locate a health care professional who can help you. The website and hotlines also provide information on which pharmacies sell emergency contraceptives because not all pharmacies carry them.
Side effects and warnings. Emergency contraceptive pills should not be used regularly as birth control because they can disrupt your menstrual cycle. They are also not 100 percent effective and can cause side effects such as nausea and vomiting, headaches, breast tenderness, dizziness and bloating. Medication may be prescribed with emergency contraceptive pills to minimize nausea and vomiting. Emergency contraceptive pills that contain only progestin cause fewer side effects.
Because emergency contraceptive pills are intended for use only as their name implies—during an emergency when other contraceptives failed or were not used—women who might otherwise not be able to take birth control pills on a regular basis may be able to use emergency contraceptive pills. Discuss your options with a health care professional.
And if you waited longer than 72 hours after unprotected sex, you have another option. An IUD can be inserted by a health care professional up to 120 hours (five days) after unprotected sex and should prevent a fertilized egg from implanting in most cases. The same precautions apply for using an IUD as an emergency contraceptive as for choosing it as a birth control method: If you are at risk for sexually transmitted diseases (if you have multiple sexual partners) or if you have a recent history of pelvic inflammatory disease, you aren't a good candidate for this type of emergency contraception.
Vaginal Contraceptive Ring
One of the newest contraceptives on the market, NuvaRing, is available by prescription only and consists of a soft, flexible, transparent ring that measures about 2 inches in diameter. It contains a combination of estrogen and progestin hormones (ethinyl estradiol and levonorgestrel). It is inserted into the vagina like a tampon, where the hormones are slowly released on a continual basis. You need to insert a new ring each month for continuous contraception. You can insert the ring yourself into your vagina, where it should remain for three weeks. Then you remove the ring for one week, during which time you have your period.
Benefits. NuvaRing only needs to be inserted once a month, making it a convenient form of birth control. And, like oral contraceptives, NuvaRing is highly effective when used according to the labeling. For every 100 women using NuvaRing correctly for an entire year, only one will become pregnant.
Side effects and warnings. Side effects of the NuvaRing may include vaginal discharge, vaginitis and irritation. Like oral contraceptives, NuvaRing may increase the risk of blood clots, heart attack and stroke. Women who use NuvaRing are strongly advised not to smoke, as it may increase the risk of heart-related side effects.
The contraceptive Ortho Evra is a transdermal (through the skin) patch approved by the FDA in 2001 that contains ethinyl estradiol and the progesterone norelgestromin. The one-and-three-quarter-inch patch is applied to the skin (abdomen, buttocks or upper torso, but not breasts) where it slowly releases hormones for a week. It must be replaced every week. After three weeks (and three new patches) you have one week that is patch-free, during which you get your period.
Benefits. The Ortho Evra patch is 91 percent effective in preventing pregnancy when used correctly. It also removes the problem of having to remember to take a pill every day or insert a device before intercourse.
Side effects and warnings. In clinical trials, the patch was less effective in women weighing more than 198 pounds. Also, some women experienced breast symptoms, headache, a reaction at the application site, nausea and emotional changes. Other risks are similar to those from using birth control pills, including an increased risk of blood clots, heart attack and stroke. Women who use Ortho Evra are strongly advised not to smoke, as it may increase the risk of heart-related side effects.
The Ortho Evra label carries an FDA-required warning that the birth control patch delivers a higher dose of estrogen than the birth control pill and therefore may increase the risk of blood clots and other serious side effects. Women taking or considering the birth control patch should talk to their health care professional about these risks.
Long-Acting Hormonal Methods
, or the low-dose form, Depo-Subq-Provera): This method provides pregnancy protection for up to three months. A health care professional injects the medication into your buttocks or upper arm muscle. You will need to return to your health care professional's office every three months for another injection to continue protection. This option may bring some changes in menstrual bleeding. Early on, you may experience spotting. Later, many women stop having periods altogether. It is OK not to have a period when using progestin shots. With this birth control method, the uterine lining doesn't grow thick enough to shed and cause menstruation.
Benefits. Progestin shots have been shown to reduce the risk of uterine (endometrial) cancer and prevent anemia and pelvic inflammatory disease.
Side effects. These may include bloating/weight gain, headaches, depression, loss of interest in sex and hair loss, and it usually takes 12 weeks before the effects of the shot disappear. It may take up to a year before normal menstrual cycles return. Some studies have shown a link between Depo-Provera and a loss of bone density, which can lead to an increased risk of osteoporosis. The bone density may not return completely after discontinuing Depo-Provera. Because this bone density loss is greater with long-term use, talk to your health care professional about another method of birth control after two years on Depo-Provera.
Implantable contraceptives (Nexplanon). Nexplanon is a matchstick-size implant that contains the progestin etonogestrel. It prevents pregnancy by stopping release of an egg from your ovary and also changes the mucus in your cervix and the lining of your uterus, which inhibit conception. A health care provider implants one rod in the inside of your upper arm. The rod may be left in place for up to three years. It must be placed and removed by a provider who has been trained to do the implants. Nexplanon replaced Nexplanon and was designed to be easier to insert and locate. It is more than 99 percent effective in preventing pregnancy, but it is not known if it is as effective in very overweight women.
You should not use Nexplanon if you are pregnant or think you may be pregnant, have or have had blood clots, have unexplained vaginal bleeding, have liver disease, have or have had breast cancer or if you are allergic to anything in Nexplanon. You should tell your health care provider about any medications you are taking (prescription, over-the-counter or herbal). Nexplanon may change your menstrual periods. They may be irregular and unpredictable throughout the time you are using Nexplanon. You may have more bleeding, less bleeding, no bleeding or spotting, and the time between periods may vary.
Benefits. Nexplanon is more than 99 percent effective in preventing pregnancy when used correctly. It removes the problem of having to remember to take a pill every day or insert a device before intercourse.
Side effects and warnings. Failure to remove Nexplanon at the end of three years may result in infertility, ectopic pregnancy or inability to stop a drug-related adverse event. Like oral contraceptives, Nexplanon may increase the risk of blood clots, heart attack and stroke. Women who use Nexplanon are strongly advised not to smoke, as it may increase the risk of heart-related side effects. Nexplanon and other progestin-only hormonal contraceptives have been associated with higher risk of ectopic pregnancy and ovarian cysts.
Other side effects may include: headache; vaginitis; weight gain; acne; breast pain; viral infections such as colds, sore throats, sinus infections or flu-like symptoms; stomach pain; painful periods; mood swings; nervousness or depression; back pain; nausea; dizziness; pain; and pain at the site of insertion.
Intrauterine devices (IUD). The IUD is a plastic, T-shaped device that is inserted by a health care professional into the uterus. One type of IUD, the ParaGard IUD, is a T-shaped piece of soft flexible plastic wrapped in copper that can be kept in place for up to 10 years. However, you shouldn't use the ParaGard IUD if you have any risk factors for pelvic inflammatory disease (PID) or have a recent history of pelvic inflammatory disease or experience heavy menstrual bleeding because a copper IUD can increase heavy bleeding.
There are also several levonorgestrel-releasing IUDs that can be left in place for several years. During that time, they slowly release a low dose of the same progestin, levonorgestrel, found in many birth control pills. The levonorgestrel thickens cervical mucus, preventing sperm from reaching an egg. It also may help reduce cramping and bleeding. Once the IUD is removed, pregnancy becomes possible almost immediately.
The three approved hormone-releasing IUDs are:
- Mirena, which can be kept in place for up to five years.
- Skyla, which is slightly smaller than Mirena and can be left in place for three years; it may not lessen bleeding or cramping.
- Liletta, which can stay in place for three years; studies continue to see if it may be effective for longer.
Although experts do not completely understand how the IUD prevents pregnancy, they believe the device works this way: It causes just enough tissue disturbances in the uterus to create an unfriendly environment for sperm. Few, if any, sperm can make it through the uterus to the fallopian tubes, so fertilization can't occur. The progestin in the progestin-releasing IUD thickens the cervical mucus and blocks sperm. The copper released by the copper-coil IUD also helps repel sperm.
Some women are reluctant to use IUDs because of the damaging effects caused by the Dalkon Shield, an IUD popular in the 1970s. That IUD was withdrawn from the market in 1975. Newer IUDs are constructed differently and are considered safe and effective for women with low risk of sexually transmitted diseases.
Benefits. IUDs are highly effective in preventing pregnancy; they also provide some protection against ectopic pregnancies. Once the IUD is inserted, it requires no care other than checking the strings attached to the IUD to ensure that it remains in place. The strings are fine threads that hang into the cervix and can be felt from the vagina.
Side effects and warnings. The most common side effects associated with ParaGard IUD use are cramping and heavy bleeding. Women using a levonorgestrel-releasing IUD may initially have irregular periods/bleeding. After a few months, periods may become lighter or stop completely.
Use of all IUDs has been associated with an increased incidence of PID, so women who have a recent history of PID or who are at high risk for contracting STDs should not use the IUD. Cramping, pain and heavy bleeding associated with IUD use in some women is most common at the time of insertion, as is the risk of PID. Menstrual-related symptoms and discomfort may subside after several months.
Barrier methods are less effective than hormonal methods but cause fewer side effects and are associated with less risk. The effectiveness of barrier forms of contraception can be increased when used with spermicide.
- The male condom. The condom is a sheath made of latex or polyurethane that is placed on the penis just prior to intercourse to prevent sperm from entering the uterus. Latex condoms, when used consistently and correctly, provide the best available means of reducing the risk of transmission of many sexually transmitted diseases (STDs), including gonorrhea, chlamydia, HIV and trichomoniasis. Condoms also can reduce the risk of genital herpes, syphilis, chancroid and human papillomavirus infection, but only when the infected areas are covered or protected by the condom, according to the United States Centers for Disease Control and Prevention.
Condoms made of lambskin, however, do not offer such protection because they have microscopic holes that may stop sperm but are large enough to allow viruses to pass through.The FDA approved the female condom in 1993. It is a soft, thin, polyurethane sheath with two flexible rings, one that contains the closed end of the sheath and is inserted into the vagina. The other ring stays outside the vagina.
- Spermicides. Spermicides are nonprescription, nonhormonal chemical products containing the active ingredient nonoxynol-9 (N-9). They can be used alone or in combination with other barrier contraceptives. Spermicides are available as foam, cream, gel, suppository and film, and, when used with other barrier contraceptives, are more effective than either method used alone.
- Diaphragms and cervical caps. These barrier contraceptives require a prescription and initial fitting by a health care professional. The diaphragm is a soft rubber dome with a flexible rim that covers the cervix. The cervical cap fits snugly on the surface of the cervix. Both devices block sperm from entering the uterus but should be used along with a spermicide.
Both the diaphragm and the cervical cap can be inserted up to six hours before intercourse and should remain in place for six to eight hours after intercourse. You must remove a diaphragm after this period of time but you can leave a cervical cap in place for up to 48 hours.
These devices are easy to insert and remove for most women, although some women can't use the cervical cap because they have an irregularly shaped cervix. Proper fit of either device is important. If you choose one of these options, see your health care professional once a year to have it replaced. Pregnancy and childbirth can change how these devices fit. You should also carefully examine your diaphragm or cervical cap before each use to be sure it is not punctured or torn.
Benefits. One benefit of the barrier method is availability: Condoms and spermicides can be purchased over the counter (without a prescription).
Side effects. Some women and men experience allergic reactions to certain spermicides or to rubber or latex used in condoms, diaphragms or cervical caps. Consult with a health care professional if you develop any symptoms after using contraception. Symptoms might include:
- Respiratory distress
- Hay fever-type reactions such as itchy, swollen eyes, runny nose and sneezing
- Asthma-type symptoms such as chest tightness, wheezing, coughing and shortness of breath
Diaphragm and spermicide use has been associated with an increased risk of urinary tract infections (UTI) and yeast infections. Emptying your bladder immediately after intercourse and removing the diaphragm after six hours may decrease your chances of developing a UTI.
- The Contraceptive Sponge. The vaginal sponge (Today), which had been withdrawn from the market, won FDA re-approval in April 2005. The one-gram sponge is available over the counter, is 80 to 91 percent effective in preventing pregnancy and contains the spermicide nonoxynol-9. It is more effective in women who haven't given birth. When moistened with water and placed in the vagina, it releases the spermicide and begins working right away and for the next 24 hours (and it can be used repeatedly within this timeframe). The sponge should be left in place for at least six hours after intercourse. Don't leave it in place for more than 30 hours.
Natural Family Planning
Natural Family Planning
Couples using this method identify a woman's most fertile period by tracking her menstrual cycle. A calendar, body temperature and physical symptoms, such as the consistency of cervical mucus, are used to determine when ovulation is likely, and you avoid intercourse during this time.
Benefits and risks. The most obvious benefit to natural family planning is that no artificial devices or hormones are used to prevent pregnancy. Little to no cost is involved. But, experts say, while these methods can work, a couple needs to be extremely motivated to use them effectively and accurately to prevent pregnancy.
Permanent Contraception (sterilization)
Permanent contraception is the most common type of contraception overall, and it is a particularly common choice for women age 35 and older. Female sterilization closes a woman's fallopian tubes by blocking, tying or cutting them so an egg cannot travel to the uterus. There are two primary forms of female sterilization: a fairly new nonsurgical implant system (sold under the brand name Essure), and the traditional tubal ligation procedure (done via laparoscopy or minilaparotomy), often called "getting your tubes tied."
- Nonsurgical permanent birth control. Sometimes called fallopian tube occlusion, the nonsurgical permanent contraception procedure can be performed in your doctor's office with local anesthesia. The Essure system uses specially designed spring-like coils called micro inserts. (Essure contains nickel and shouldn't be used by women with a nickel allergy.) During the procedure, your doctor uses a special instrument called a hysteroscope to place the insert through your vagina and cervix into the opening of your fallopian tube in your uterus. There is no incision. Within three months, the insert causes your body to form a tissue barrier that prevents sperm from reaching the egg. During this three-month period, you need to use another form of birth control. After three months, you have to return to your doctor's office for a special x-ray to make sure your tubes are completely blocked. In clinical studies, most women reported little to no pain and were able to return to their normal activities in a day or two. In 2016, the FDA ordered changes in the package labeling for Essure to include a boxed warning and a "patient checklist," both designed to ensure that women understand the risks and benefits of the device. The FDA is also requiring Bayer, the manufacturer of Essure, to conduct a clinical study to determine risks of Essure for particular women. The government agency has received about 10,000 complaints about Essure since its release in 2002.
- Tubal ligation. With this type of sterilization procedure, your fallopian tubes are blocked with a ring or burned or clipped shut. This procedure is typically performed under general anesthesia in a hospital. It can be done via a laparoscopy or a minilaparotomy.
- Laparoscopy:The surgeon makes a small incision through the abdomen and inserts a special instrument called a laparoscope to view the pelvic region and tubes. He or she then closes the tubes using clips, tubal rings or electrocoagulation (using an electric current to cauterize and destroy a portion of the tube). The patient can usually go home the same day and resume intercourse as soon as it's comfortable. Risks include pain, bleeding, infection and other postsurgical complications, as well as an ectopic, or tubal, pregnancy.
- Minilaparotomy.During a minilaparotomy, the surgeon makes a small incision (about two inches long) and ties and cuts the tubes without the use of a viewing instrument. In general, minilaparotomy is a good choice for women who undergo sterilization right after childbirth. Patients usually need a few days to recover and can resume intercourse after consulting with their doctors.
Vasectomy. Male sterilization is called a vasectomy. This procedure is performed in the doctor's office. The scrotum is numbed with an anesthetic, so the doctor can make a small incision to access the vas deferens, the tubes through which sperm travels from the testicle to the penis. The doctor then seals, ties or cuts the vas deferens. Following a vasectomy, a man continues to ejaculate, but the fluid does not contain sperm. Temporary swelling and pain are common side effects of surgery. A newer approach to this procedure can reduce swelling and bleeding.
Benefits and risks. Sterilization is a highly effective way to permanently prevent pregnancy—it's considered more than 99 percent effective, meaning less than one woman in 100 will get pregnant after having a sterilization procedure. However, a vasectomy is not effective for about three months; a doctor will perform a sperm test to determine when the vasectomy can be relied on to prevent pregnancy. Surgery for female sterilization is more complex and carries greater risk than surgery to sterilize men, and recovery takes longer. Reversing sterilization in men and women is extremely difficult, however, and often unsuccessful. There is a small possibility of getting pregnant after sterilization; some evidence suggests that women who are younger when they are sterilized have a higher risk of getting pregnant.
Couples who are not sure about sterilization but want to postpone having children for at least five to 10 years should first consider using long-acting contraceptive methods such as IUDs or hormonal shots or implants before choosing sterilization.
Facts to Know
Facts to Know
Many women do not get the protection they expect from their birth control methods because they do not use the methods correctly. Nearly half of women using birth control experience unplanned pregnancies, even though many methods are nearly 100 percent effective when used properly.
Birth control pills, also called oral contraceptives, are now available in a variety of low-dose options that are safe and effective for most healthy women. Birth control pills include combination pills, which contain estrogen and progestin, and a "mini-pill" option that does not contain estrogen.
Oral contraceptives may reduce the risk of ovarian and uterine cancers and provide other health benefits such as regulating menstrual cycles; one brand of oral contraceptives has been shown to be effective for treating symptoms associated with premenstrual syndrome.
When used consistently and correctly, condoms offer the best available means of reducing the risk of infection from the following STDs: gonorrhea, chlamydia and trichomoniasis. Condoms can also reduce the risk of genital herpes, syphilis, chancroid and HPV infection, but only when the infected areas are covered or protected by the condom.
Women who have medical or religious concerns about artificial birth control methods can use fertility awareness methods, sometimes called natural family planning. These methods require that couples be motivated and adhere to a schedule that avoids sex when a woman is ovulating and most likely to be fertile.
According to the Guttmacher Institute, seven in 10 teens have had intercourse by their 19th birthday. A sexually active teenager who doesn't use contraception has a 90 percent chance of becoming pregnant within one year. Studies show that teens who talk to their parents about sex, pregnancy, birth control and sexually transmitted diseases are less likely to become sexually active at an early age and more likely to use protection when they do have sex.
Sterilization is the second most popular form of birth control in the United States, right after the pill. It is considered a permanent form of birth control.
It can be helpful to review your contraceptive options as you age to make sure your current birth control method continues to fit your lifestyle and reproductive health needs.
Questions to Ask
Questions to Ask
Review the following Questions to Ask about contraception so you're prepared to discuss this important health issue with your health care professional.
How effective is this contraceptive option, and how do I use it correctly? What are its risks and benefits for me?
(For implantable contraceptives): Do you have experience in inserting the implant? Will it hurt me? After it's inserted, will it be visible?
What is the difference between the old and new IUDs? Are the new IUDs really safer to use?
Should I consider the pill? What are its advantages and disadvantages?
What is the difference between barrier devices like the diaphragm and cervical cap and the vaginal ring? What is the ring and how does it work?
Does this contraception option protect me from AIDS or other sexually transmitted diseases?
If I want to consider permanent contraception, what are my options?
Questions To Ask Yourself
How important is it to you and your partner that you do not become pregnant at this time?
What is the likelihood that you and your partner will be able to follow the requirements of the contraceptive method you choose?
Do you take medication or have a medical condition that might make some contraceptives a poor choice for you?
Do you smoke?
How often do you have intercourse?
How old are you? Do you have children, or do you want to have children some day?
Will your health insurance pay for your contraceptive choice? If not, can you afford it long term?
What do I do if I miss a day of taking my birth control pills?
The pills you have to worry most about missing are the ones right before and right after the seven placebo pills in your pack. Known as the pill-free interval, the placebos are designed to be taken the week you have your period to help you stay in the rhythm of taking a pill every day. If you start a new pack late or take longer than seven days "pill free," you might ovulate and could become pregnant. Read the package insert that came with your pills; it will explain what to do about missed pills. Or call your health care professional. In the meantime, use backup contraception just to be safe. In general, if you miss a pill, take it as soon as you remember and then continue taking one pill each day as prescribed (depending on when you missed your pill, you may take two pills on the same day). If you miss two or more pills in the first week of your pill cycle and you have unprotected intercourse during this week, consider using emergency contraception. If you miss pills in the fourth week of a 28-day pack, those pills are likely placebo if you're using a 21/7 regimen. However, some of the newer formulations may contain active pills, so read the package insert for instructions.
I've heard that I can't get pregnant while I'm breastfeeding. Does that mean I don't need a contraceptive?
The lactational amenorrhea method (LAM) refers to the natural cessation of a woman's menstrual period while she is breastfeeding. Ovulation doesn't occur at this time, so birth control is automatic. LAM is only effective in preventing pregnancy if the mother is breastfeeding exclusively; her baby is less than six months old; and the mother's periods have not yet returned. If a woman starts to get her period again, it's a pretty good indication that she's ovulating and able to get pregnant. But, in general, even though breastfeeding does provide some contraceptive protection, it is not a completely reliable form of contraception. There are several birth control options that are safe for breastfeeding women and their babies, so why take chances? Here are your options:
The mini-pill is a progestin-only pill that usually has no negative impact on milk production (combination pills can dry up milk) and may even provide a little boost in milk volume. You can start this pill right after delivery under the guidance of your health care professional.
Nonhormonal contraception methods such as barrier devices and copper IUDs are preferred in women who are nursing because they don't contain hormones that could affect milk supply or pass through the milk. If hormonal methods are the only option, progestin-only birth control is preferred in women who are breast-feeding.
Barrier methods such as condoms and spermicides have no impact on breastfeeding and may be helpful in overcoming vaginal dryness caused by breastfeeding (use lubricated condoms). They can be used immediately postpartum. If you want to use a diaphragm or cervical cap, wait until after your sixth postpartum week; diaphragms and cervical caps need to be fitted after you completely heal, and it's not advisable to use them until you've stopped bleeding.
You can have an IUD inserted between six and eight weeks postpartum.
I've been taking birth control pills for several years. Do I need to give my body a rest and stop taking them for a while?
There is no scientific evidence that taking oral contraceptives does any long-term harm to your endocrine system, which regulates hormones.
My partner hates to use condoms because he says they make sex less pleasurable. Is there anything else I can do to protect myself from STDs?
You could try the female condom, which has a looser fit. There are also male condoms designed to enhance pleasure, which are sold over the counter.
You might try a few things to make condom use more fun. How about unrolling it onto your partner's penis yourself?
Condoms sometimes help men maintain an erection; tell your partner you want to use a condom so sex will last longer. If all else fails, refuse to have sex with him if he doesn't use a condom or find other ways to enjoy each other sexually. (Keep in mind that avoiding penis-vagina contact is the only way to stay safe from pregnancy, but other sexual acts, such as oral sex, still put you at risk for some STDs.)
How do I keep a condom from slipping?
First, check during sex that the condom is still where it should be. Second, make sure your partner knows to withdraw soon after ejaculation, before the penis gets smaller. And third, while he is withdrawing, he should hold the rim of the condom.
I've heard that birth control pills cause cancer, but I've also heard they can protect against cancer. Which is true?
Newer low-estrogen birth control pills do not carry the risk of increased breast cancer that higher-dose estrogen pills did. An August 2014 study published in Cancer Research that looked at breast cancer risk and birth control pill use in women ages 20 to 49 found breast cancer risk was higher in women who had previously taken high-dose estrogen birth control pills, but not in women who had taken low-dose estrogen pills.
There is also evidence, however, that use of birth control pills decreases the incidence of uterine, ovarian and possibly colorectal cancer. The longer a woman uses the pill, the more her risk of developing these cancers is reduced. Birth control pills may also protect against developing breast and ovarian cysts. Discuss the risks and benefits of birth control pills with your health care professional.
I've had all the children I want, but I'm not ready for sterilization. I've been considering the IUD. Is it safe?
Yes. The fears surrounding intrauterine devices (IUDs) stem mainly from problems with the Dalkon Shield, an IUD introduced in the 1970s. The construction of the Dalkon Shield increased the risk of bacterial infections, which resulted in pelvic inflammatory disease for many women. Today's IUDs are constructed differently and are safe and highly effective. IUDs are not good options for women at risk for contracting sexually transmitted infections, however.
I am 16 years old and would like to use birth control pills. The problem is that I smoke cigarettes. My mom used to smoke and was told she couldn't use them. Can I?
In women younger than 35, the benefits of birth control pills appear to outweigh the risks, even in heavy smokers, unless there is a family history of blood clots. However, smoking puts you at risk for numerous serious health problems, including cancer and heart disease, so you should talk to your health care professional about ways to help you kick the habit.
Organizations and Support
Organizations and Support
ASHA's STI Resource Center Hotline
Address: American Social Health Association
P.O. Box 13827
Research Triangle Park, NC 27709
Address: 834 Chestnut Street, Suite 400
Philadelphia, PA 19107
Emergency Contraception Hotline
Address: Office of Population Research
Princeton University, Wallace Hall
Princeton, NJ 08544
Hotline: 1-888-NOT-2-LATE (1-888-668-2528)
National Abortion and Reproductive Rights Action League (NARAL)
Address: 1156 15th Street, NW, Suite 700
Washington, DC 20005
National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention
Address: Centers for Disease Control and Prevention
1600 Clifton Road
Atlanta, GA 30333
Hotline: 1-800-CDC-INFO (1-800-232-4636)
Email: [email protected]
Planned Parenthood Federation of America
Address: 434 West 33rd Street
New York, NY 10001
Hotline: 1-800-230-PLAN (1-800-230-7526)
Sexuality Information and Education Council of the United States (SIECUS)
Address: 90 John Street, Suite 704
New York, NY 10038
A Gynecologist's Second Opinion: The Questions & Answers You Need to Take Charge of Your Health
by William H. Parker, Rachel L. Parker
All About Birth Control: A Complete Guide
by Jon Knowles
by Miriam Stoppard
Sexual Health Questions You Have...Answers You Need
by Michael V. Reitano, Charles Ebel
The Whole Truth About Contraception: A Guide to Safe and Effective Choices
by MD, MPH Beverly Winikoff, Suzanne Wymelenberg
The Yale Guide to Women's Reproductive Health: From Menarche to Menopause
by Mary Jane Minkin, Carol V. Wright
Association of Reproductive Health Professionals
1901 L Street, NW, Suite 300
Washington, DC 20036
Email: [email protected]
Center for Young Women's Health
Address: Center for Young Women's Health
333 Longwood Avenue, 5th Floor
Boston, MA 02115
"FDA takes additional action to better understand safety of Essure, inform patients of potential risks. " U.S. Food and Drug Administration. February 29, 2016. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm488313.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery. Accessed March 1, 2016.
"FDA orders 'black box' warning label on Essure long-acting contraceptive." MedlinePlus, HealthDay article. February 29, 2016. https://www.nlm.nih.gov/medlineplus/news/fullstory_157520.html. Accessed March 1, 2016.
Nexplanon website. http://www.nexplanon.com/en/consumer/. Accessed December 8, 2015.
Liletta website. https://www.liletta.com/. Accessed December 8, 2015.
Skyla website. http://www.skyla-us.com/. Accessed December 8, 2015.
"Unintended pregnancy in the United States." The Guttmacher Institute. February 2015. http://www.guttmacher.org/pubs/FB-Unintended-Pregnancy-US.html. Accessed May 2015.
"FDA approves Plan B One-Step emergency contraceptive for use without a prescription for all women of child-bearing potential." U.S. Food and Drug Administration. June 2013. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm358082.htm. Accessed April 2015.
"Today Sponge." Planned Parenthood. 2014. http://www.plannedparenthood.org/learn/birth-control/birth-control-sponge-today-sponge. Accessed May 2015.
"Is there a link between birth control pills and higher breast cancer risk?" Breastcancer.org. August 2014. http://www.breastcancer.org/research-news/study-questions-birth-control-and-risk. Accessed May 2015.
Edlow, AG et al. "Hormonal Contraceptive Options for Women with Headache: A Review of the Evidence." Rev Ostet Gynecol. Spring 2010. 3(20): 55-65. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938905/
"Contraception." U.S. Centers for Disease Control and Prevention. April 2015. http://www.cdc.gov/reproductivehealth/unintendedpregnancy/contraception.htm. Accessed May 2015.
"Contraceptive Use in the United States." The Guttmacher Institute. February 2014. http://www.guttmacher.org/pubs/fb_contr_use.html. Accessed May 2015.
"Pull out method." Planned Parenthood. 2014. http://www.plannedparenthood.org/learn/birth-control/withdrawal-pull-out-method. Accessed May 2015.
"2011 Women’s Health Stats and Facts." ACOG. http://webcache.googleusercontent.com/search?q=cache:JbVurrV5anYJ:www.acog.org/-/media/NewsRoom/MediaKit.pdf+&cd=11&hl=en&ct=clnk&gl=us. Accessed May 2015.
The Emergency Contraception Website. Office of Population Research at Princeton University and the Association of Reproductive Health Professionals. http://ec.princeton.edu/index.html. Accessed January 9, 2012.
"Ovarian Cancer Overview." The American Cancer Society. June 2011.
http://www.cancer.org/Cancer/OvarianCancer/OverviewGuide/ovarian-cancer-overview-prevention. Accessed October 2011.
"Breast Cancer Risk Factors." The American Cancer Society. September 2011. http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/breast-cancer-risk-factors. Accessed October 2011.
Adiana website. http://www.adiana.com. Accessed March 16, 2011.
"Overview of contraception." Uptodate.com. Updated February 2009. Subscription necessary to view text. Accessed March 2009.
"Risks and side effects associated with estrogen-progestin contraceptives." Uptodate.com. Updated February 2009. Subscription necessary to view text. Accessed March 2009.
"Mirena patient information." http://berlex.bayerhealthcare.com/html/products/pi/mirena_patient_insert.pdf. Accessed March 2009.
"Birth control and family planning." Medline, the National Institutes of Health. December 2008. http://www.nlm.nih.gov/medlineplus/ency/article/001946.htm. Accessed March 2009.
"Ortho Evra." www.orthoevra.com. Accessed March 2009.
"Seasonale and Seasonique." www.seasonale.com. Accessed March 2009.
"Birth Control Pill Use Cuts Ovarian Cancer Risk." The American Cancer Society. January 2008. http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Birth_Control_Pill_Use_Cuts_Ovarian_Cancer_Risk.asp. Accessed March 2009.
"Barrier methods of contraception." The American College of Obstetricians and Gynecologists. July 2008. http://www.acog.org/publications/patient_education/bp022.cfm. Accessed March 2009.
"Lactational amenorrhea." The Mayo Clinic. July 2008. http://www.mayoclinic.com/health/lactational-amenorrhea/BI00030. Accessed March 2009.
"What causes endometrial cancer?" The American Cancer Society. August 2008. http://www.cancer.org/docroot/CRI/content/CRI_2_2_2x_What_causes_endometrial_cancer.asp?sitearea=. Accessed March 2009.
"Birth control options for women—female sterilization." The University of Maryland Medical Center. November 2008. http://www.umm.edu/patiented/articles/what_female_sterilization_000091_9.htm. Accessed March 2009.
McSwain H, Brodie MF. Fallopian tube occlusion, an alternative to tubal ligation. Tech Vasc Interv Radiol. 2006 Mar;9(1):24-9.
Essure Web site. Available at www.essure.com. Accessed April 8, 2007.
"Colorectal Cancer Statistics 2005." Cancer Research and Prevention Foundation. http://www.preventcancer.org/colorectal/press/2k3statistics.cfm. Accessed June 13, 2005.
"Efforts to Research and Inform the Public About Nonoxynol-9 and HIV." U.S. Government Accountability Office (GAO). Report to Congressional Requesters. Publication GAO-05-399. March 2005. http://www.global-campaign.org/clientfiles/GAO_report_0405.pdf. Accessed June 12, 2005.
"FDA Approves Seasonale Oral Contraceptive" FDA Talk Paper. U.S. Food and Drug Administration. September 5, 2003. http://www.fda.gov/bbs/topics/ANSWERS/2003/ANS01251.html. Accessed June 11, 2005.
Hatcher RA, Zieman M, Nelson A, et al. "Managing Contraception." BTG Foundation. http://www.managingcontraception.com/pdfmanage.html. Accessed June 11, 2005.
"Birth Control: Comparing the Choices." Association of Reproductive Health Professionals (ARHP). Updated October 30, 2004. http://www.arhp.org/patienteducation/onlinebrochures/comparing/index.cfm?ID=279. Accessed June 12, 2005
"Oral Contraceptives and Cancer Risk." National Cancer Institute. Reviewed February 2003. Includes CARE and Collaborative Group on Hormonal Factors in Breast Cancer Study findings. http://cis.nci.nih.gov/fact/3_13.htm. Accessed June 12, 2005.
"FDA Approves First Hormonal Vaginal Contraceptive Ring." FDA Talk Paper. U.S. Food and Drug Administration. October 3, 2001. http://www.fda.gov/bbs/topics/ANSWERS/2001/ANS01107.html. Accessed June 11, 2005.
"FDA Approves First Hormonal Contraceptive Skin Patch." FDA Talk Paper. U.S. Food and Drug Administration. Nov. 20, 2001. http://www.fda.gov/bbs/topics/ANSWERS/2001/ANS01119.html. Accessed June 11, 2005.
"Ortho Evra® (norelgestromin/ethyl estradiol transdermal system)" Ortho McNeil Pharmaceuticals. http://www.orthoevra.com/. Accessed June 12, 2005.
Hatcher R., Trussell J, Stewart F, et al. 2004. Contraceptive technology (18th ed). New York: Ardent Media, Inc.
"What causes breast cancer?" The American Cancer Society. September 16, 2005. http://www.cancer.org/docroot/CRI/content/CRI_2_2_2X_What_causes_breast_cancer_5.asp?sitearea=CRI. Accessed December 2005.
"Class II Special Controls Guidance Document: Labeling for Male Condoms Made of Natural Rubber Latex." U.S. Food and Drug Administration. November 14, 2005. http://www.fda.gov/cdrh/comp/guidance/1548.html. Accessed December 2005.
Hatcher R, et al. (2004). Contraceptive technology (18th ed). New York: Ardent Media Inc.
"FDA approves new indication for YAZ to treat emotional and physical symptoms of premenstrual dysphoric disorder." Berlex. October 2006.
Last date updated: Tue 2016-03-01
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