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Age of Woman's First Menstruation May Signal Higher Risk of Heart Disease

Age of Woman's First Menstruation May Signal Higher Risk of Heart Disease

By Stacey Feintuch

Created: 10/31/2019
Last Updated: 10/31/2019

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Women who experienced their first menstruation at an early or late age have a higher risk of developing "major adverse cardiac events," like heart attack, stroke, heart failure and death, according to recent research co-authored by University of Florida Health researcher Carl J. Pepine, M.D, with collaborators at Cedars-Sinai Medical Center in Los Angeles. Their study, published in Journal of the American Heart Association, found that women whose first menstruation (menarche) was at age 10 or younger had a four-fold higher risk of adverse cardiac events. That is compared with those whose menarche occurred at the U.S. average of age 12. For women whose menarche came at age 15 or later, the risk was elevated two-and-a-half times. Women whose menarche occurred at ages 11, 13 or 14 also faced at least a two-fold increased risk of heart problems, according to the research.

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