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Mary Jane Minkin, MD

Clinical Professor

Obstetrics, Gynecology, and Reproductive Sciences

Yale University School of Medicine

Mary Jane Minkin, MD, is clinical professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences at the Yale University School of Medicine, and has been in private practice in New Haven (CT) for more than 35 years. Dr. Minkin is board-certified in obstetrics and gynecology, and she practices at Yale-New Haven Hospital. She earned her medical degree from Yale Medical School and her undergraduate degree from Brown University.

She did both her internship and residency at Yale-New Haven Hospital, the former in internal medicine, the latter in obstetrics and gynecology. She is a fellow of the American Congress of Obstetricians and Gynecologists (FACOG), and has been a North American Menopause Society Certified Menopause Practitioner (NCMP) since 2002. Dr. Minkin has been Director of the Sexuality, Intimacy and Menopause clinic in the Division of Gynecological Oncology, in the Smilow cancer center at Yale New Haven Hospital since 2008. She has also been Director of the Yale Obstetrical and Gynecological Society (YOGS) since its inception in 2006.

She serves on numerous committees, notably for more than 25 years as Faculty Representative of the Department of Obstetrics and Gynecology on the Yale-New Haven Hospital Pharmacy and Therapeutics Committee, on the Yale Infection Control Committee, and on the Yale Antibiotic Drug Utilization Committee. She also serves on the residency selection committee.

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Woman with hot water bottle healing stomach pain

Ask the Expert: What Causes Painful Periods?

OB-GYN Dr. Mary Jane Minkin explains period pain

Your Health

If you don’t like to say the words “painful periods,” you can just say “dysmenorrhea”— it will sound better, perhaps, but you'll still be uncomfortable. So let’s talk about what’s causing the pain and how you can make it better.

Let’s first discuss the difference between primary dysmenorrhea and secondary dysmenorrhea. Primary dysmenorrhea is sort of your garden variety menstrual cramps, caused by chemicals that the uterus makes that lead to cramping. Secondary dysmenorrhea is caused by abnormalities of the pelvic organs, which lead to cramps.

So let’s dig deeper into primary dysmenorrhea. The nasty chemicals that cause the cramps are prostaglandins, and they’re made by the uterus around the time of our periods. Remember that the uterus is a muscle, and these prostaglandins cause that muscle to contract. They also can cause the smooth muscles of our gastrointestinal tract to contract, so some women experience nausea and diarrhea. Prostaglandins can also cause fever and achiness, although those symptoms are a bit less common.

And importantly, we tend to make more prostaglandins during menstrual cycles in which we ovulate.

How do we help primary dysmenorrhea? We can take medications that block the production of more prostaglandins — and if you’re someone with regular cycles, you can even start taking these medicines (called “prostaglandin synthetase inhibitors”) the day before your period starts. Once the prostaglandins are there, they do their nasty work, so take these meds early!

And where do you get these medicines? At your corner supermarket or pharmacy: They may have fancy names, but they include ibuprofen and naproxen, and even aspirin. And, maybe you noticed that I said you make more of these nasty chemicals when you ovulate — so how do you not ovulate?

You can take a combined hormonal contraceptive (birth control) that works by blocking ovulation, and you can also take ibuprofen with it. And don’t worry about disrupting your body’s prostaglandin production: Next cycle, that uterus will still produce plenty of prostaglandins.

Of course, regular exercise is very helpful, too, as is eating a healthy diet. But if all these things don’t seem to be helping enough, check in with your gynecological care provider because this could mean you have secondary dysmenorrhea. Problems like endometriosis and fibroids can also cause cramping, and your provider will work with you to investigate whether those issues could be contributing — and then figure out how to help.

Dr. Mary Jane Minkin is clinical professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences at the Yale University School of Medicine; host of the podcast “menopause:unumted”; and has been in private practice for more than 35 years. She’s on a mission to destigmatize women’s health issues, especially menopause.

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